Cyclic-di-GMP | B2045

Cyclic di-GMP (c-di-GMP) is one of the most important and common bacterial second messenger. It is involved in numerous prokaryotic processes, including biofilm formation, motility, virulence, and cell cycling. c-di-GMP also has functions in eukaryotic cells. It is detected by the transmembrane protein stimulator of interferon genes (STING), leading to activation of the innate immune system.

Cyclic di-GMP (c-di-GMP) is one of the most important and common bacterial second messenger. It is involved in numerous prokaryotic processes, including biofilm formation, motility, virulence, and cell cycling. c-di-GMP also has functions in eukaryotic cells. It is detected by the transmembrane protein stimulator of interferon genes (STING), leading to activation of the innate immune system.

B2045 | Cyclic-di-GMP DataSheet

Alternate Name/Synonyms: Guanylyl-(3'→5')-3'-guanylic acid, cyclic nucleotide; Cyclic diguanylate; 3',5'-Cyclic diguanylic acid; c-di-GMP

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 61093-23-0

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₀H₂₄N₁₀O₁₄P₂

Molecular Weight: 690.41

Cell-Permeable?: Yes

Purity: ≥95%

Solubilities: H₂O (1 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A STING ligand

MDL Number: N/A

PubChem CID: 6323195

SMILES: C1C2C(C(C(O2)N3C=NC4=C3NC(=NC4=O)N)O)OP(=O)(OCC5C(C(C(O5)N6C=NC7=C6NC(=NC7=O)N)O)OP(=O)(O1)O)O

InChi: InChI=1S/C20H24N10O14P2/c21-19-25-13-7(15(33)27-19)23-3-29(13)17-9(31)11-5(41-17)1-39-45(35,36)44-12-6(2-40-46(37,38)43-11)42-18(10(12)32)30-4-24-8-14(30)26-20(22)28-16(8)34/h3-6,9-12,17-18,31-32H,1-2H2,(H,35,36)(H,37,38)(H3,21,25,27,33)(H3,22,26,28,34)/t5-,6-,9-,10-,11-,12-,17-,18-/m1/s1

InChi Key: PKFDLKSEZWEFGL-MHARETSRSA-N