Cyclin A (CCNA2) Antibody (N-term) [APR05876G]

Cyclin A (CCNA2) Antibody (N-term) [APR05876G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This Cyclin A (CCNA2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-84 amino acids from the N-terminal region of human Cyclin A (CCNA2) .

Cellular Localisation: Nucleus. Cytoplasm. Note=Exclusively nuclear during interphase (PubMed:1312467) . Detected in the nucleus and the cytoplasm at prophase (PubMed:1312467) . Cytoplasmic when associated with SCAPER (PubMed:17698606) .

Molecular Weight: 48551

Clone: Polyclonal

Gene Name: CCNA2 (HGNC:1578)

Gene ID: 890

Function: Cyclin which controls both the G1/S and the G2/M transition phases of the cell cycle. Functions through the formation of specific serine/threonine protein kinase holoenzyme complexes with the cyclin- dependent protein kinases CDK1 or CDK2. The cyclin subunit confers the substrate specificity of these complexes and differentially interacts with and activates CDK1 and CDK2 throughout the cell cycle.

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: IHC-P, FC, WB

Dilution: WB--1:2000 IHC-P--1:100~500 FC--1:10~50

Synonyms: Cyclin-A2, Cyclin-A, CCNA2, CCN1, CCNA