Cyclin A2 polyclonal Antibody | BS90353

Cyclin A2 polyclonal Antibody | BS90353 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Application: WB ICC/IF IHC

Application Range: WB:1:1,000-1:2,000 ICC:1:100-1:500 IHC:1:50-1:200

Background: The critical role that the family of regulatory proteins known as cyclins play in eukaryotic cell cycle regulation is well established. The best-characterized cyclin complex is the mitotic cyclin B/Cdc2 p34 kinase, the active component of maturing promoting factor. Cyclin A accumulates prior to cyclin B in the cell cycle, appears to be involved in control of S phase and has been shown to associate with cyclin- dependent kinase-2 (Cdk2) . In addition, cyclin A has been implicated in cell transformation and is found in complexes with E1A, transcription factors DRTF1 and E2F and retinoblastoma protein, p110. A second form of cyclin A, named cyclin A1 because of its high sequence homology to Xenopus cyclin A1, is most highly expressed in germ cells. It has been proposed that cyclin A1 can associate with Cdk2, p39 and Cdc2 p34.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: Cyclin A2 polyclonal Antibody detects endogenous levels of Cyclin A2 protein.

Molecular Weight: 49 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Cyclin-A, CCNA2, CCN1, CCNA, Ccna2, CCNA2, Cyclin A2, Cyclin-A, Cyclin-A2,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: