Cyclophilin B monoclonal Antibody | BS65500M

Cyclophilin B monoclonal Antibody | BS65500M | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human,Mouse,Rat,

Application: WB

Application Range: WB=1:1000-10000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

Background: The cyclophilins are a conserved class of proteins that bind the immunosuppressive drug cyclosporin A (CsA) with high affinity. CsA blocks helper T-cell activation at a step between T-cell receptor stimulation and the transcriptional activation of cytokine genes. Cyclophilins from many species possess peptidyl-prolyl cis-trans isomerase (PPIase) activity that is blocked by CsA and therefore may be relevant in CsA-mediated immunosuppression.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Cyclophilin B monoclonal Antibody detects endogenous levels of Cyclophilin B protein.

Molecular Weight: ~20 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Cphn 2; Cphn2; CyP 20b; CYP S1; CYP-S1; CYPB; MGC14109; MGC2224; peptidyl prolyl cis trans isomerase B; Peptidyl prolyl cis trans isomerase B precursor; Peptidyl-prolyl cis-trans isomerase B precursor; Peptidylprolyl isomerase B; PPIase; PPIB; Rotamase; S cyclophilin; SCYLP; PPIB_HUMAN.

Immunogen: KLH conjugated synthetic peptide derived from human Cyclophilin B

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: affinity purified by Protein G

Pathway: