CYCS Polyclonal Antibody | E-AB-40209

CYCS Polyclonal Antibody | E-AB-40209 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Cytochrome C, Somatic, CYC, Cytochrome C, THC4, HCS.

Application: WB, IHC

Reactivity: Human, Bovine

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cell Biology, Cardiovascular, Metabolism, Signal Transduction

Background: Cytochrome c is a 12-15 kDa electron transporting protein located in the inner mitochondrial membrane. Upon apoptotic stimulation, cytochrome c can be released from mitochondria into cytoplasm, resulting in caspase-3 activation and apoptosis. Measurement of cytochrome c release from the mitochondria is useful for detection of the onset of apoptosis in cells. In addition, cytochrome c can also leave cells and be detectable in extra-cellular medium of apoptotic cells and serum of cancer patients. The level of serum cytochrome c may serve as a prognostic maker during cancer therapy.

Concentration: 2 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant Human Cytochrome c protein

Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Purification Method: Affinity purification

Dilution: WB 1:1000-1:2000 IHC 1:100-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 12 kDa

Molecular Weight(Observed): 12 kDa