CYP2A7 polyclonal Antibody | BS5683

CYP2A7 polyclonal Antibody | BS5683 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IHC ICC

Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200 ICC: 1:50~1:200

Background: The cytochrome P450 proteins (CYPs) are monooxygenases that catalyze reactions involved in both drug metabolism and in the synthesis of cholesterol, steroids and other lipids. P450 enzymes are classified into subfamilies, such as CYP1A and CYP2A, based on their sequence similarities. CYP2A7 (cytochrome P450 2A7), also known as CPA7, CPAD, CYPIIA7 or P450-IIA4, is a 494 amino acid peripheral membrane protein that belongs to the CYP2A subfamily of cytochrome P450 proteins. Localized to the endoplasmic reticulum, CYP2A7 can be induced to high levels in liver in response to foreign compounds, such as carcinogens, pesticides and drugs. CYP2A7 functions as a hydroxylase that uses a heme group to catalyze the oxidation of target flavoproteins.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CYP2A7 polyclonal Antibody detects endogenous levels of CYP2A7 protein.

Molecular Weight: ~ 56 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Cytochrome P450 2A7; CYPIIA7; Cytochrome P450 IIA4

Immunogen: Synthetic peptide, corresponding to amino acids 435-480 of Human CYP2A7.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: