CYSLTR1 Polyclonal Antibody | E-AB-67309

CYSLTR1 Polyclonal Antibody | E-AB-67309 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: CYSLTR1, CYSLT1, CYSLT1R, CYSLTR, HMTMF81

Application: WB

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Neuroscience

Background: This gene encodes a member of the G-protein coupled receptor 1 family. The encoded protein is a receptor for cysteinyl leukotrienes, and is involved in mediating bronchoconstriction via activation of a phosphatidylinositol-calcium second messenger system. Activation of the encoded receptor results in contraction and proliferation of bronchial smooth muscle cells, eosinophil migration, and damage to the mucus layer in the lung. Upregulation of this gene is associated with asthma and dysregulation may also be implicated in cancer. Alternative splicing results in multiple transcript variants.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: A synthetic peptide of human CYSLTR1 (NP_006630.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 38 kDa

Molecular Weight(Observed): 38 kDa