Cytoglobin polyclonal Antibody | BS8529

Cytoglobin polyclonal Antibody | BS8529 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IF

Application Range: WB: 1:500~1:2000 IF: 1:50~1:200

Background: Hemoglobin, myoglobin, neuroglobin, and cytoglobin belong to the globin family, porphyrin-containing proteins that function in oxygen transport and storage. Myoglobin contributes to intracellular oxygen storage and transcellular facilitated diffusion of oxygen in skeletal and cardiac muscle. Neuroglobin is an oxidative stress-responsive sensor for signal transduction in the brain. Hemoglobin contributes to oxygen storage and diffusion of oxygen in blood tissue. Cytoglobin (also designated histoglobin), is a ubiquitous protein that facilitates diffusion of oxygen through tissues and acts as a scavenger for nitric oxide or other reactive oxygen species. It binds O2 via its heme and also has a protective function during oxidative stress. Cytoglobin, a hexacoordinate hemoglobin, shares less than 30% identity with other human hemoglobins and is widely expressed in a wide array of tissues including fibroblasts and nerve cell populations.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Cytoglobin polyclonal Antibody detects endogenous levels of Cytoglobin protein.

Molecular Weight: ~ 21kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Histoglobin; HGb; Stellate cell activation-associated protein; CYGB; STAP

Immunogen: Recombinant full length Human Cytoglobin.

Conjugate: N/A

Modification: N/A

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: N/A