Cytokeratin 5 polyclonal Antibody | BS90383

Cytokeratin 5 polyclonal Antibody | BS90383 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Application: WB IHC

Application Range: WB:1:1,000 IHC:1:50-1:200

Background: Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation which is directly applicable to the characterization of malignant tumors. Cytokeratin 5 is expressed in normal basal cells. Mutations of the cytokeratin 5 gene (KRT5) have been shown to result in the autosomal dominant disorder epidermolysis bullosa (EB) .

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: Cytokeratin 5 polyclonal Antibody detects endogenous levels of Cytokeratin 5 protein.

Molecular Weight: 62 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: CK-5, K5, KRT5, 58 kDa cytokeratin, CK-5, CK5, Cytokeratin-5, Cytokeratin5, DDD, DDD1, EBS2, epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types, K2C5, K5, keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types), Keratin 5, Keratin, keratin complex 2, basic, gene 5, keratin, type II cytoskeletal 5, Keratin-5, Keratin5, KRT 5, Krt5, KRT5A, type II cytoskeletal 5, Type-II keratin Kb5,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: