CZC-8004 | B1868

CZC-8004 is a pan-specific kinase inhibitor that binds to a range of tyrosine kinases, including ABL, BTK, FAK, FER, JAK1, SRC, SYK, TEC, TNK1, TYK2, and YES. It inhibits these kinases at low micromolar concentrations and can be coupled to sepharose via its amino side chain for affinity chromatography applications.

CZC-8004 is a pan-specific kinase inhibitor that binds to a range of tyrosine kinases, including ABL, BTK, FAK, FER, JAK1, SRC, SYK, TEC, TNK1, TYK2, and YES. It inhibits these kinases at low micromolar concentrations and can be coupled to sepharose via its amino side chain for affinity chromatography applications.

B1868 | CZC-8004 DataSheet

Alternate Name/Synonyms: N2-​[4-​(aminomethyl)​phenyl]​-​5-​fluoro-​N4-​phenyl-2,​4-​pyrimidinediamine

Appearance: Off-white solid

Formulation: N/A

CAS Number: 916603-07-1

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: N/A

Molecular Formula: C₁₇H₁₆FN₅

Molecular Weight: 309.3

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>30 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A pan-specific kinase inhibitor

MDL Number: N/A

PubChem CID: 15980598

SMILES: C1=CC=C(C=C1)NC2=NC(=NC=C2F)NC3=CC=C(C=C3)CN

InChi: InChI=1S/C17H16FN5/c18-15-11-20-17(22-14-8-6-12(10-19)7-9-14)23-16(15)21-13-4-2-1-3-5-13/h1-9,11H,10,19H2,(H2,20,21,22,23)

InChi Key: UKOHFWNBTUJMMN-UHFFFAOYSA-N