D-64131 | B1066

D-64131 is a potent tubulin polymerization inhibitor. Cytotoxic and inhibits tumor cell proliferation in vitro (IC₅₀ = 74 nM). Antimitotic agent. Induces G2/M cell cycle arrest.

D-64131 is a potent tubulin polymerization inhibitor. Cytotoxic and inhibits tumor cell proliferation in vitro (IC₅₀ = 74 nM). Antimitotic agent. Induces G2/M cell cycle arrest.

B1066 | D-64131 DataSheet

Alternate Name/Synonyms: (5-Methoxy-1H-indol-2-yl)phenylmethanone

Appearance: Yellow solid

Formulation: N/A

CAS Number: 74588-78-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₆H₁₃NO₂

Molecular Weight: 251.28

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>20 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent tubulin polymerization inhibitor

MDL Number: MFCD04039791

PubChem CID: 3921152

SMILES: COC1=CC2=C(C=C1)NC(=C2)C(=O)C3=CC=CC=C3

InChi: InChI=1S/C16H13NO2/c1-19-13-7-8-14-12(9-13)10-15(17-14)16(18)11-5-3-2-4-6-11/h2-10,17H,1H3

InChi Key: ICMIJSRDISNKOC-UHFFFAOYSA-N