D (+)-Cycloserine | B1188

D-Cycloserine is a partial agonist at the glycine modulatory site of NMDA glutamatergic receptors. Blocks kainate-induced seizures and displays anticonvulsant effects in rat models. D-Cycloserine facilitates synaptic plasticity but impairs glutamatergic neurotransmission in rat hippocampal slices. Second-line drug for the treatment of tuberculosis. Enhances activity-dependent plasticity in human adults.

D-Cycloserine is a partial agonist at the glycine modulatory site of NMDA glutamatergic receptors. Blocks kainate-induced seizures and displays anticonvulsant effects in rat models. D-Cycloserine facilitates synaptic plasticity but impairs glutamatergic neurotransmission in rat hippocampal slices. Second-line drug for the treatment of tuberculosis. Enhances activity-dependent plasticity in human adults.

B1188 | D (+)-Cycloserine DataSheet

Alternate Name/Synonyms: (R)-4-Amino-3-isoxazolidone; ; Orientomycin; Oxamycin

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 68-41-7

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: N/A

Molecular Formula: C₃H₆N₂O₂

Molecular Weight: 102.09

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (100 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A partial agonist at the glycine modulatory site of NMDA glutamatergic receptors

MDL Number: MFCD00005353

PubChem CID: 6234

SMILES: C1C(C(=O)NO1)N

InChi: InChI=1S/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6)/t2-/m1/s1

InChi Key: DYDCUQKUCUHJBH-UWTATZPHSA-N