D-Dimer, Human Plasma | P1434

The D-dimer antigen is a unique marker of fibrin degradation that is formed by the sequential action of 3 enzymes: thrombin, factor XIIIa, and plasmin. Thus D-dimer is not normally found in serum or plasma, but is present only if fibrinolysis has occurred and is, therefore, an excellent marker of the breakdown of a blood clot. The measurement of D-dimer in serum samples (s-DD) after standardized coagulation has been reported as a possible single global test for fibrinolysis in unstimulated conditions in healthy subjects and in patients with ischemic heart disease and with different metabolic disorders.

P1434 | D-Dimer, Human Plasma DataSheet

Biomolecule/Target :

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Taglines: A fibrin degradation product used as a marker of venous thromboembolism

NCBI Gene ID #: 2243, 2244, 2266

NCBI Gene Symbol: FGA, FGB, FGG

Gene Source: Human

Accession #: P02671, P02675, P02679

Recombinant: False

Source: Human Plasma

Purity by SDS-PAGE: >95%

Assay: SDS-PAGE

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Unit Definition:

Molecular Weight: ~184 kDa

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Appearance: Liquid protein

Physical form description: Liquid

Reconstitution Instructions:

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Handling: Centrifuge the vial prior to opening.

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