D4DR polyclonal Antibody | BS6997

D4DR polyclonal Antibody | BS6997 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Mouse,Rat

Application: WB IHC

Application Range: WB 1:500 - 1:1000 IHC 1:50 - 1:200

Background: This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats.DRD4 expression has been reported in various regions of the brain as well as in adrenal gland, artery, eye, heart, kidney, placenta, spinal cord, testis, and vas deferens.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: D4DR polyclonal Antibody detects endogenous levels of D4DR protein.

Molecular Weight: ~50 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: D (4) dopamine receptor; D (2C) dopamine receptor; Dopamine D4 receptor; DRD4

Immunogen: Recombinant full length Human D4DR.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: