Daclatasvir dihydrochloride | B2224

Daclatasvir is a highly selective inhibitor of HCV NS5A with EC₅₀ of 9-50 pM, for a broad range of HCV replicon genotypes and the JFH-1 genotype 2a infectious virus in cell culture.

Daclatasvir is a highly selective inhibitor of HCV NS5A with EC₅₀ of 9-50 pM, for a broad range of HCV replicon genotypes and the JFH-1 genotype 2a infectious virus in cell culture.

B2224 | Daclatasvir dihydrochloride DataSheet

Alternate Name/Synonyms: methyl N-[(2S)-1-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2S)-2-(methoxycarbonylamino)-3-methylbutanoyl]pyrrolidin-2-yl]-1H-imidazol-5-yl]phenyl]phenyl]-1H-imidazol-2-yl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate;dihydrochloride; BMS 790052-05

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 1009119-65-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₄₀H₅₀N₈O₆·2HCl

Molecular Weight: 811.8

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A highly selective HCV NS5A inhibitor

MDL Number: N/A

PubChem CID: 25154713

SMILES: CC(C)C(C(=O)N1CCCC1C2=NC=C(N2)C3=CC=C(C=C3)C4=CC=C(C=C4)C5=CN=C(N5)C6CCCN6C(=O)C(C(C)C)NC(=O)OC)NC(=O)OC.Cl.Cl

InChi: InChI=1S/C40H50N8O6.2ClH/c1-23(2)33(45-39(51)53-5)37(49)47-19-7-9-31(47)35-41-21-29(43-35)27-15-11-25(12-16-27)26-13-17-28(18-14-26)30-22-42-36(44-30)32-10-8-20-48(32)38(50)34(24(3)4)46-40(52)54-6;;/h11-18,21-24,31-34H,7-10,19-20H2,1-6H3,(H,41,43)(H,42,44)(H,45,51)(H,46,52);2*1H/t31-,32-,33-,34-;;/m0../s1

InChi Key: BVZLLUDATICXCI-JMSCDMLISA-N