DBeQ | 1858

Cell- permeable. A potent, selective, reversible, and ATP-competitive p97 inhibitor. DBeQ blocks both ubiquitin-dependent and autophagic protein clearance pathways and rapidly promotes executioner caspases -3 and -7.

DBeQ is a potent, selective, reversible, and ATP-competitive p97 inhibitor. DBeQ blocks both ubiquitin-dependent and autophagic protein clearance pathways and rapidly promotes executioner caspases -3 and -7.

1858 | DBeQ DataSheet

Alternate Name/Synonyms: N², N⁴-Dibenzylquinazoline-2,4-diamine

Appearance: Colorless solid

Formulation: N/A

CAS Number: 177355-84-9

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₂H₂₀N₄

Molecular Weight: 340.42

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (~ 25 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A p97 inhibitor

MDL Number: MFCD03691820

PubChem CID: 676352

SMILES: C1=CC=C(C=C1)CNC2=NC(=NC3=CC=CC=C32)NCC4=CC=CC=C4

InChi: InChI=1S/C22H20N4/c1-3-9-17(10-4-1)15-23-21-19-13-7-8-14-20(19)25-22(26-21)24-16-18-11-5-2-6-12-18/h1-14H,15-16H2,(H2,23,24,25,26)

InChi Key: QAIMUUJJAJBPCL-UHFFFAOYSA-N