DBT monoclonal Antibody | MB62980

DBT monoclonal Antibody | MB62980 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: FC, IF, WB

Application Range: WB 1:2000, FLOW 1:100

Background: The branched-chain alpha-keto acid dehydrogenase complex (BCKD) is an inner-mitochondrial enzyme complex involved in the breakdown of the branched-chain amino acids isoleucine, leucine, and valine. The BCKD complex is thought to be composed of a core of 24 transacylase (E2) subunits, and associated decarboxylase (E1), dehydrogenase (E3), and regulatory subunits. This gene encodes the transacylase (E2) subunit. Mutations in this gene result in maple syrup urine disease, type 2. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: dihydrolipoamide branched chain transacylase E2

Molecular Weight: 46.4 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: BCATE2; BCKAD-E2; BCKADE2; BCOADC-E2; E2; E2B

Immunogen: Full length human recombinant protein of human DBT (NP_001909) produced in HEK293T cell.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A