DCLRE1C Polyclonal Antibody | E-AB-67686

DCLRE1C Polyclonal Antibody | E-AB-67686 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: DCLRE1C, A-SCID, DCLREC1C, RS-SCID, SCIDA, SNM1C

Application: WB, IF

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: N/A

Background: This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The encoded protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in this gene can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative splicing results in multiple transcript variants.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human DCLRE1C (NP_001029027.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000 IF 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 49 kDa/64 kDa/65 kDa/78 kDa

Molecular Weight(Observed): 45 kDa