DCNP1 Antibody | 7769

DCNP1 Antibody | 7769 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: DCNP1 antibody was raised against an 18 amino acid peptide near the amino terminus of human DCNP1.
The immunogen is located within the first 50 amino acids of DCNP1.

Research Area: Immunology

Tested Application: E, WB, IHC-P, IF

Application: DCNP1 antibody can be used for detection of DCNP1 by Western blot at 1 - 2 μg/ml. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Specificiy: DCNP1 antibody is human, mouse and rat reactive.

Positive Control 1: Cat. No. 1407 - Mouse Skeletal Muscle Tissue Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 27 kDa
Observed: 24 kDa

Validation: N/A

Isoform: N/A

Purification: DCNP1 antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: DCNP1 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: DCNP1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: DCNP1 Antibody: DCNP1, C5orf20, Dendritic cell nuclear protein 1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The DCNP1 (dendritic cell nuclear protein 1) gene is specifically expressed in dendritic cells, potent antigen-presenting cells involved in activating naive T cells to initiate antigen-specific immune response (1) . It is localized mainly in the perinucleus. One of the alleles (A/T) of this gene causes premature translation termination at aa 117 and has been associated with an increased prevalence of major depression in humans (2, 3) . DCNP1 may play a role in the pathogenesis of depressive disorders by enhancing corticotropin-releasing hormone expression in the hypothalamic paraventricular nucleus (4) .