DDC Polyclonal Antibody | E-AB-19409

DDC Polyclonal Antibody | E-AB-19409 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: AADC, Aromatic L Amino Acid Decarboxylase, Aromatic-L-amino-acid decarboxylase, DDC, DDC_HUMAN, DOPA decarboxylase (aromatic L-amino acid decarboxylase), DOPA decarboxylase

Application: WB, IHC, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Neuroscience, Cancer, Metabolism

Background: The encoded protein catalyzes the decarboxylation of L-3, 4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Concentration: 1.5 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human DDC

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 54 kDa

Molecular Weight(Observed): Refer to figures