DDX24 polyclonal Antibody | BS61138

DDX24 polyclonal Antibody | BS61138 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: DEAD-box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure and ribosome/spliceosome assembly. Based on their distribution patterns, some members of this family may be involved in embryogenesis, spermatogenesis and cellular growth and division. DDX24 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 24) is an 859 amino acid protein that contains one helicase C-terminal domain and one helicase ATP-binding domain. Expressed ubiquitously with highest levels in brain and heart, DDX24 functions as an ATP-dependent RNA helicase that is subject to DNA damage-dependent phosphorylation. Human DDX24 shares 79% sequence similarity with its mouse counterpart, suggesting a conserved role between species.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: DDX24 polyclonal Antibody detects endogenous levels of DDX24 protein.

Molecular Weight: ~ 90 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: ATP-dependent RNA helicase DDX24 (EC:3.6.4.13) ; DEAD box protein 24; DDX24

Immunogen: A synthetic peptide corresponding to residues in Human DDX24.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: