DEF Antibody (N-term) [APR03621G]

DEF Antibody (N-term) [APR03621G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, Ha, M

Specificity: This DEF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2-30 amino acids from the N-terminal region of human DEF.

Cellular Localisation: Nucleus, nucleolus

Molecular Weight: 87055

Clone: Polyclonal

Gene Name: UTP25 (HGNC:28440)

Gene ID: 27042

Function: Component of the ribosomal small subunit processome for the biogenesis of ribosomes, functions in pre-ribosomal RNA (pre-rRNA) processing (By similarity) . Essential for embryonic development in part through the regulation of p53 pathway. Controls the expansion growth of digestive organs and liver (PubMed:25007945, PubMed:27657329, PubMed:23357851) . Also involved in the sympathetic neuronal development (By similarity) . Mediates, with CAPN3, the proteasome-independent degradation of p53/TP53 (PubMed:23357851, PubMed:27657329) .

Summary: Tissue Location: Expressed in colon..

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: IHC-P, IF, WB, FC

Dilution: WB--1:2000

Synonyms: Digestive organ expansion factor homolog, DIEXF, C1orf107, DEF