DEFA1 Polyclonal Antibody | E-AB-12365

DEFA1 Polyclonal Antibody | E-AB-12365 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: DEF1, DEF3, DEFA1, DEFA2, DEFA3, Defensin alpha 1, Defensin alpha 2, Defensin alpha 3, HNP1, HNP3, HP1, HP3, MRS, Neutrophil defensin 1, Neutrophil defensin 2, Neutrophil defensin 3

Application: WB, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Immunology, Microbiology

Background: Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation.

Concentration: 0.4 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human DEFA1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:1000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 10 kDa

Molecular Weight(Observed): N/A