Deferoxamine Mesylate | 1883

An iron chelator used for the treatment of acute iron intoxication and of chronic iron overload due to transfusion-dependent anemias. Has been shown to have anti-proliferative effects on vascular smooth muscle cells in vitro and in vivo and to arrest cells in the G1 phase. Induces apoptosis in HL-60 cells by chelating iron. In addition, it has been shown to have antioxidant properties and to protect cells against H₂O₂-induced damage.

Deferoxamine Mesylate is an iron chelator used for the treatment of acute iron intoxication and of chronic iron overload due to transfusion-dependent anemias. Has been shown to have anti-proliferative effects on vascular smooth muscle cells in vitro and in vivo and to arrest cells in the G1 phase. I

1883 | Deferoxamine Mesylate DataSheet

Alternate Name/Synonyms: DFOM, Deferoxamine methanesulfonate salt, Desferrioxamine mesylate salt

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 138-14-7

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₅H₄₈N₆O₈·CH₄O₃S

Molecular Weight: 656.79

Cell-Permeable?: No

Purity: ≥98% by HPLC

Solubilities: H₂O (~ 50 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: An iron chelator

MDL Number: MFCD00058605

PubChem CID: 62881

SMILES: CC(=O)N(CCCCCNC(=O)CCC(=O)N(CCCCCNC(=O)CCC(=O)N(CCCCCN)O)O)O.CS(=O)(=O)O

InChi: InChI=1S/C25H48N6O8.CH4O3S/c1-21(32)29(37)18-9-3-6-16-27-22(33)12-14-25(36)31(39)20-10-4-7-17-28-23(34)11-13-24(35)30(38)19-8-2-5-15-26;1-5(2,3)4/h37-39H,2-20,26H2,1H3,(H,27,33)(H,28,34);1H3,(H,2,3,4)

InChi Key: IDDIJAWJANBQLJ-UHFFFAOYSA-N