Delamanid | 2280

Delamanid is a new antituberculosis drug that inhibits mycolic acid synthesis and has shown potent in vitro and in vivo activity against drug-resistant strains of Mycobacterium tuberculosis.

Delamanid is a new antituberculosis drug that inhibits mycolic acid synthesis and has shown potent in vitro and in vivo activity against drug-resistant strains of Mycobacterium tuberculosis.

2280 | Delamanid DataSheet

Alternate Name/Synonyms: (2R)-2-Methyl-6-nitro-2-[(4-{4-[4-(trifluoromethoxy)phenoxy]piperidin-1-yl}phenoxy)methyl]-2,3-dihydroimidazo[2,1-b]oxazole

Appearance: White solid

Formulation: N/A

CAS Number: 681492-22-8

Structure Available?: Yes

Peptide sequence: No

Salt Form: No

Molecular Formula: C₂₅H₂₅F₃N₄O₆

Molecular Weight: 534.48

Cell-Permeable?: Yes

Purity: ³99% ee by HPLC and >99% by LC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: An antituberculosis agent

MDL Number: N/A

PubChem CID: 6480466

SMILES: CC1(CN2C=C(N=C2O1)[N+](=O)[O-])COC3=CC=C(C=C3)N4CCC(CC4)OC5=CC=C(C=C5)OC(F)(F)F

InChi: InChI=1S/C25H25F3N4O6/c1-24(15-31-14-22(32(33)34)29-23(31)38-24)16-35-18-4-2-17(3-5-18)30-12-10-20(11-13-30)36-19-6-8-21(9-7-19)37-25(26,27)28/h2-9,14,20H,10-13,15-16H2,1H3/t24-/m1/s1

InChi Key: XDAOLTSRNUSPPH-XMMPIXPASA-N