DENND1B Polyclonal Antibody | E-AB-18656

DENND1B Polyclonal Antibody | E-AB-18656 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: C1ORF18, C1orf218 , Chromosome 1 open reading frame 218, Connecdenn 2, DEN1B, DENN domain containing protein 1B, DENN domain-containing protein 1B, DENN MADD domain containing 1B, DENND1B, DKFZp547O0715, FAM31B , Family with sequence similarity 31 member B, FLJ20054, FLJ21179 , FLJ33888, MGC103810, MGC27044, Protein FAM31B, RP11 53I24.2

Application: WB, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cell Biology

Background: Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery.

Concentration: 0.54 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Fusion protein of human DENND1B

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 86 kDa

Molecular Weight(Observed): Refer to figures