DEP1 Polyclonal Antibody | BS65603

DEP1 Polyclonal Antibody | BS65603 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat,Rabbit,

Application: WB,

Application Range: WB=1:500-2000 

Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: DEP1 Polyclonal Antibody detects endogenous levels of DEP1 protein.

Molecular Weight: 60 kD

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: CD 148; CD148; CD148 antigen; Density enhanced phosphatase 1; Density-enhanced phosphatase 1; DEP 1; DEP-1; HPTP eta; HPTPeta; Human density enhanced phosphatase 1; Protein tyrosine phosphatase eta; Protein tyrosine phosphatase receptor type J; Protein tyrosine phosphatase receptor type J polypeptide; Protein-tyrosine phosphatase eta; Protein-tyrosine phosphatase receptor type J; PTPJ; Ptprj; PTPRJ_HUMAN; R PTP Eta; R-PTP-eta; R-PTP-J; Receptor type tyrosine protein phosphatase eta; Receptor-type tyrosine-protein phosphatase eta; SCC 1; SCC1.  

Immunogen: KLH conjugated synthetic peptide derived from human PTPRJ:865-970/1337 

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: affinity purified by Protein A

Pathway: