DEPDC1 Antibody (N-term) [APR05646G]

DEPDC1 Antibody (N-term) [APR05646G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This DEPDC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-38 amino acids from the N-terminal region of human DEPDC1.

Cellular Localisation: Nucleus. Note=Colocalizes with ZNF224 at the nucleus

Molecular Weight: 92960

Clone: Polyclonal

Gene Name: DEPDC1

Gene ID: 55635

Function: May be involved in transcriptional regulation as a transcriptional corepressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells.

Summary: Tissue Location: Expressed in testis. Up-regulated in bladder cancer cells (at protein level) .

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, IHC-P

Dilution: WB--1:1000

Synonyms: DEP domain-containing protein 1A, DEPDC1, DEPDC1A