DHCR24 Polyclonal Antibody | E-AB-15380

DHCR24 Polyclonal Antibody | E-AB-15380 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: 24 dehydrocholesterol reductase, 24-dehydrocholesterol reductase, 3 beta hydroxysterol delta 24 reductase, 3-beta-hydroxysterol delta-24-reductase, DCE, Delta(24)-sterol reductase, Desmosterol to cholesterol enzyme, DHC24, Dhcr24, Diminuto dwarf1 homolog, Diminuto/dwarf1 homolog, KIAA0018, Nbla03646, Seladin-1, SELADIN1, Selective AD indicator 1, Selective Alzheimer's Disease Indicator 1

Application: IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cell Biology, Cardiovascular, Metabolism, Neuroscience

Background: This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.

Concentration: 0.7 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human DHCR24

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:30-1:150

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A