DHCR7 Antibody (C-term) [APR07556G]

DHCR7 Antibody (C-term) [APR07556G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This DHCR7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 437-463 amino acids from the C-terminal region of human DHCR7.

Cellular Localisation: Endoplasmic reticulum membrane; Multi-pass membrane protein

Molecular Weight: 54489

Clone: Polyclonal

Gene Name: DHCR7

Gene ID: 1717

Function: 7-dehydrocholesterol reductase of the cholesterol biosynthetic pathway reducing the C7-C8 double bond of cholesta-5, 7- dien-3beta-ol (7-dehydrocholesterol/7-DHC) and cholesta-5, 7, 24-trien- 3beta-ol, two intermediates in that pathway.

Summary: Tissue Location: Widely expressed. Most abundant in adrenal gland, liver, testis, and brain.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, IHC-P, IF

Dilution: WB--1:2000

Synonyms: 7-dehydrocholesterol reductase, 7-DHC reductase, Putative sterol reductase SR-2, Sterol Delta (7) -reductase, DHCR7, D7SR