Didanosine | B2702

Didanosine is a nucleoside analog that acts as a reverse transcriptase inhibitor (NRTI) with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Didanosine is phosphorylated to active metabolites that compete for incorporation into viral DNA. They inhibit the HIV reverse transcriptase enzyme competitively and act as a chain terminator of DNA synthesis. Didanosine is effective against HIV, and usually used in combination with other antiviral therapy.

Didanosine is a nucleoside analog that acts as a reverse transcriptase inhibitor (NRTI) with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Didanosine is phosphorylated to active metabolites that compete for incorporation into viral DNA. They inhibit the HIV reverse transcriptase enzyme competitively and act as a chain terminator of DNA synthesis. Didanosine is effective against HIV, and usually used in combination with other antiviral therapy.

B2702 | Didanosine DataSheet

Alternate Name/Synonyms: DDI,9-((2R,5S)-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-1H-purin-6(9H)-one,2,3-Dideoxyinosine

Appearance: White to off-white solid

Formulation:

CAS Number: 69655-05-6

Structure Available?:

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₀H₁₂N₄O₃

Molecular Weight: 236.23

Cell-Permeable?: TRUE

Purity: ≥98%

Solubilities: ~10 mg/ml DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A nucleoside analog with antiviral properties

MDL Number: MFCD00077728

PubChem CID: 135398739

SMILES: C1CC(OC1CO)N2C=NC3=C2N=CNC3=O

InChi: InChI=1S/C10H12N4O3/c15-3-6-1-2-7(17-6)14-5-13-8-9(14)11-4-12-10(8)16/h4-7,15H,1-3H2,(H,11,12,16)/t6-,7+/m0/s1

InChi Key: BXZVVICBKDXVGW-NKWVEPMBSA-N