DIDO1 Antibody | 22-235

DIDO1 Antibody | 22-235 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human DIDO1 (NP_071388.2) .

Research Area: Apoptosis, Cell Cycle

Tested Application: WB, IF

Application: WB: 1:500 - 1:2000
IF: 1:20 - 1:50

Specificiy: N/A

Positive Control 1: HT-29

Positive Control 2: MCF7

Positive Control 3: HepG2

Positive Control 4: BT-474

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 76kDa/244kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: DIDO1, BYE1, DIO1, DATF1, DIDO2, DIDO3, DIO-1, DATF-1, C20orf158, dJ885L7.8

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Apoptosis, a major form of cell death, is an efficient mechanism for eliminating unwanted cells and is of central importance for development and homeostasis in metazoan animals. In mice, the death inducer-obliterator-1 gene is upregulated by apoptotic signals and encodes a cytoplasmic protein that translocates to the nucleus upon apoptotic signal activation. When overexpressed, the mouse protein induced apoptosis in cell lines growing in vitro. This gene is similar to the mouse gene and therefore is thought to be involved in apoptosis. Alternatively spliced transcripts have been found for this gene, encoding multiple isoforms.