DiMethyl-DNMT3A-K44 pAb | 16-374

DiMethyl-DNMT3A-K44 pAb | 16-374 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: A synthetic dimethylated peptide around K44 of mouse DNMT3A (NP_031898.1) .

Research Area: Other

Tested Application: IF

Application: IF: 1:50 - 1:200

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: MmuIIIA, DNA (cytosine-5) -methyltransferase 3A, DNA MTase MmuIIIA, DNA methyltransferase MmuIIIA

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.