Diosmetin | B1922

Diosmetin is a natural flavonoid that displays anticancer, antimicrobial, antioxidant, estrogenic and anti-inflammatory activity. It reversibly inhibits cytochrome P450 (CYP) isoforms 1A1 and 1B1 in human liver microsomes with Ki values of 89 and 16 nM, respectively. Diosmetin also activates BMP signaling.

Diosmetin is a natural flavonoid that displays anticancer, antimicrobial, antioxidant, estrogenic and anti-inflammatory activity. It reversibly inhibits cytochrome P450 (CYP) isoforms 1A1 and 1B1 in human liver microsomes with Ki values of 89 and 16 nM, respectively. Diosmetin also activates BMP signaling.

B1922 | Diosmetin DataSheet

Alternate Name/Synonyms: 5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one; Disometol

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 520-34-3

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₆H₁₂O₆

Molecular Weight: 300.3

Cell-Permeable?: Yes

Purity: ≥98%

Solubilities: DMSO (~30 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: Cytochrome P450 (CYP) inhibitor

MDL Number: MFCD00017425

PubChem CID: 5281612

SMILES: COC1=C(C=C(C=C1)C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O

InChi: InChI=1S/C16H12O6/c1-21-13-3-2-8(4-10(13)18)14-7-12(20)16-11(19)5-9(17)6-15(16)22-14/h2-7,17-19H,1H3

InChi Key: MBNGWHIJMBWFHU-UHFFFAOYSA-N