LBD
DLG2 Antibody (Center) [APR11740G]
- SKU:
- LBD-APR11740G
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Description
DLG2 Antibody (Center) [APR11740G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: M, Rat
Specificity: This DLG2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 614-648 amino acids from the Central region of human DLG2.
Cellular Localisation: Cell membrane {ECO:0000250|UniProtKB:Q63622}; Lipid-anchor {ECO:0000250|UniProtKB:Q63622}. Cell junction, synapse, postsynaptic density {ECO:0000250|UniProtKB:Q63622}. Cell junction, synapse. Membrane {ECO:0000250|UniProtKB:Q63622}. Cell projection, axon {ECO:0000250|UniProtKB:Q63622}. Perikaryon {ECO:0000250|UniProtKB:Q63622}. Note=Concentrated in soma and postsynaptic density of a subset of neurons {ECO:0000250|UniProtKB:Q63622}
Molecular Weight: 97552
Clone: Polyclonal
Gene Name: DLG2
Gene ID: 1740
Function: Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses (By similarity) .
Summary: N/A
Form: N/A
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: Disks large homolog 2, Channel-associated protein of synapse-110, Chapsyn-110, Postsynaptic density protein PSD-93, DLG2