DLK1 Antibody | 7017

DLK1 Antibody | 7017 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: DLK1 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human DLK1.
The immunogen is located within amino acids 260 - 310 of DLK1.

Research Area: Stem Cell

Tested Application: E, WB, ICC, IF

Application: DLK1 antibody can be used for detection of DLK1 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Specificiy: At least four isoforms of DLK1 are known to exist.

Positive Control 1: Cat. No. 1211 - HepG2 Cell Lysate

Positive Control 2: Cat. No. 17-011 - Hep G2 Cell Slide

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 42 kDa

Validation: N/A

Isoform: N/A

Purification: DLK1 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: DLK1 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: DLK1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: DLK1 Antibody: DLK, Protein delta homolog 1, pG2, DLK-1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: DLK1 Antibody: The Delta-like 1 homolog (DLK1) is a transmembrane protein containing six epidermal growth factor repeats. It is involved in the differentiation of several cell types, including adipocytes and is also thought to be a tumor suppressor. The DLK1 gene is one of several imprinted genes located in a region on chromosome 14q32; certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14) . DLK1 is expressed from the paternal allele; a polymorphism within this gene has been associated with child and adolescent obesity.