DLL4 Antibody [APR33634G]

DLL4 Antibody [APR33634G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: M, Rat

Specificity: This DLL4 antibody is generated from a rabbit immunized with a recombinant protein from the human region of human DLL4.

Cellular Localisation: Cell membrane; Single-pass type I membrane protein

Molecular Weight: 74605

Clone: Polyclonal

Gene Name: DLL4

Gene ID: 54567

Function: Involved in the Notch signaling pathway as Notch ligand (PubMed:11134954) . Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting (PubMed:20616313) . Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types (By similarity) . During spinal cord neurogenesis, inhibits V2a interneuron fate (PubMed:17728344) .

Summary: Tissue Location: Expressed in vascular endothelium.

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: Delta-like protein 4, Drosophila Delta homolog 4, Delta4, DLL4