DLX1 Antibody (Center) [APR33569G]

DLX1 Antibody (Center) [APR33569G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This DLX1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 84-118 amino acids from the Central region of human DLX1.

Cellular Localisation: Nucleus.

Molecular Weight: 27320

Clone: Polyclonal

Gene Name: DLX1

Gene ID: 1745

Function: Plays a role as a transcriptional activator or repressor (PubMed:14671321) . Inhibits several cytokine signaling pathways, such as TGFB1, activin-A/INHBA and BMP4 by interfering with the transcriptional stimulatory activity of transcription factors, such as MSX2, FAST2, SMAD2 and SMAD3 during hematopoietic cell differentiation (PubMed:14671321) . Plays a role in terminal differentiation of interneurons, such as amacrine and bipolar cells in the developing retina (By similarity) . Likely to play a regulatory role in the development of the ventral forebrain (By similarity) . May play a role in craniofacial patterning and morphogenesis and may be involved in the early development of diencephalic subdivisions (By similarity) .

Summary: Tissue Location: Expressed in hematopoietic cell lines.

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB, FC

Dilution: FC--1:25 WB--1:2000

Synonyms: Homeobox protein DLX-1, DLX1