DMGDH Polyclonal Antibody | E-AB-17889

DMGDH Polyclonal Antibody | E-AB-17889 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Dimethylglycine dehydrogenase, Dimethylglycine dehydrogenase, mitochondrial, Dmgdh, M2GD, ME2GLYDH, mitochondrial

Application: WB, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Metabolism, Neuroscience, Signal Transduction

Background: This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants.

Concentration: 2.1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human DMGDH

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 97 kDa

Molecular Weight(Observed): Refer to figures