DNA Ligase IV polyclonal Antibody | BS90417

DNA Ligase IV polyclonal Antibody | BS90417 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB IHC ICC

Application Range: WB:1:500-1:2,000 IHC:1:50-1:200 ICC:1:10-1:50

Background: The X-ray repair cross-complementing protein XRCC4 and DNA Ligase IV are essential for repairing double-strand breaks in DNA. These stories form a critical complex composed of two molecules of each protein that preferentially bind DNA with nicks or broken ends. As an obligatory accessory molecule, XRCC4 binds to DNA Ligase IV and enhances its joining activity. The XRCC4 / DNA Ligase IV complex is also involved in V (D) J recombination. V (D) (in) a pair of high incidence of apoptosis in the development nervous system and a block in B and T cell maturation.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: DNA Ligase IV polyclonal Antibody detects endogenous levels of DNA Ligase IV protein.

Molecular Weight: 104 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: LIG4, DNA ligase IV ATP dependent, DNA joinase, DNA ligase 4, DNA ligase IV, DNA repair enzyme, DNLI4, LIG 4, LIG4, LIG4S, Ligase IV, Ligase IV DNA ATP dependent, Polydeoxyribonucleotide synthase [ATP] 4, Polydeoxyribonucleotide synthase 4, Polydeoxyribonucleotide synthase, Polynucleotide ligase, Sealase,

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: