DNAJB4 monoclonal Antibody | MB63037

DNAJB4 monoclonal Antibody | MB63037 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: WB

Application Range: WB 1:500~2000

Background: The protein encoded by this gene is a molecular chaperone, tumor suppressor, and member of the heat shock protein-40 family. The encoded protein binds the cell adhesion protein E-cadherin and targets it to the plasma membrane. This protein also binds incorrectly folded E-cadherin and targets it for endoplasmic reticulum-associated degradation. This gene is a strong tumor suppressor for colorectal carcinoma, and downregulation of it may serve as a good biomarker for predicting patient outcomes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: DnaJ heat shock protein family (Hsp40) member B4

Molecular Weight: 37.6 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: DjB4; DNAJW; HLJ1

Immunogen: Human recombinant protein fragment corresponding to amino acids 2-337 of human DNAJB4 (NP_008965) produced in E.coli.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A