DOC2A Antibody (Center) [APR31028G]

DOC2A Antibody (Center) [APR31028G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This DOC2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277-306 amino acids from the Central region of human DOC2A.

Cellular Localisation: Lysosome. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein. Cell junction, synapse, synaptosome

Molecular Weight: 43959

Clone: Polyclonal

Gene Name: DOC2A

Gene ID: 8448

Function: Calcium sensor which most probably regulates fusion of vesicles with membranes. Binds calcium and phospholipids. May be involved in calcium dependent neurotransmitter release through the interaction with UNC13A. May be involved in calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Regulates Ca (2+) -dependent secretory lysosome exocytosis in mast cells.

Summary: Tissue Location: Predominantly expressed in brain. Also expressed in testis.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: FC, WB, IHC-P

Dilution: FC--1:10~50 WB--1:1000 IHC-P--1:100~500

Synonyms: Double C2-like domain-containing protein alpha, Doc2, Doc2-alpha, DOC2A