DOCK2 Polyclonal Antibody | E-AB-67583

DOCK2 Polyclonal Antibody | E-AB-67583 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: DOCK2, IMD40

Application: WB

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: N/A

Background: The protein encoded by this gene belongs to the CDM protein family. It is specifically expressed in hematopoietic cells and is predominantly expressed in peripheral blood leukocytes. The protein is involved in remodeling of the actin cytoskeleton required for lymphocyte migration in response to chemokine signaling. It activates members of the Rho family of GTPases, for example RAC1 and RAC2, by acting as a guanine nucleotide exchange factor (GEF) to exchange bound GDP for free GTP.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human DOCK2 (NP_004937.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: WB 1:500-1:1000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 38 kDa/211 kDa

Molecular Weight(Observed): 240 kDa