DOCK8 monoclonal Antibody | MB63047

DOCK8 monoclonal Antibody | MB63047 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: WB

Application Range: WB 1:2000

Background: This gene encodes a member of the DOCK180 family of guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with Rho GTPases and are components of intracellular signaling networks. Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: dedicator of cytokinesis 8

Molecular Weight: 238.3 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: HEL-205; MRD2; ZIR8

Immunogen: Human recombinant protein fragment corresponding to amino acids 84-405 of human DOCK8 (NP_982272) produced in E.coli.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A