DOK1 Polyclonal Antibody | E-AB-10290

DOK1 Polyclonal Antibody | E-AB-10290 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Docking protein 1 62kD, Docking protein 1, DOK 1, DOK1, DOK1, Downstream of tyrosine kinase 1, p62(dok), P62DOK, pp62

Application: WB, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cardiovascular, Metabolism, Signal Transduction

Background: The protein encoded by this gene is part of a signal transduction pathway downstream of receptor tyrosine kinases. The encoded protein is a scaffold protein that helps form a platform for the assembly of multiprotein signaling complexes. Two transcript variants encoding different isoforms have been found for this gene. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.

Concentration: 0.5 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human DOK1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 52 kDa

Molecular Weight(Observed): N/A