Dovitinib | B1614

Dovitinib (TKI258, CHIR258) is a multitargeted RTK inhibitor

Dovitinib (TKI258, CHIR258) is a multitargeted RTK inhibitor

B1614 | Dovitinib DataSheet

Alternate Name/Synonyms: Dovitinib, CHIR-258; CHIR 258; CHIR258; 1-amino-5-fluoro-3-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)quinolin-2(1H)-one; (3Z)-4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1,3-dihydrobenzimidazol-2-ylidene]quinolin-2-one; TKI258; TKI-258; TKI 258 ; Multitargeted RTK inhibitor

Appearance: Solid

Formulation: N/A

CAS Number: 405169-16-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₁H₂₁FN₆O

Molecular Weight: 392.43

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (30 mg/mL)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A multitargeted RTK inhibitor

MDL Number: MFCD10565680

PubChem CID: 9886808

SMILES: CN1CCN(CC1)C2=CC3=C(C=C2)NC(=C4C(=C5C(=NC4=O)C=CC=C5F)N)N3

InChi: 1S/C21H21FN6O/c1-27-7-9-28(10-8-27)12-5-6-14-16(11-12)25-20(24-14)18-19(23)17-13(22)3-2-4-15(17)26-21(18)29/h2-6,11,24-25H,7-10,23H2,1H3/b20-18-

InChi Key: KCOYQXZDFIIGCY-ZZEZOPTASA-N