Doxorubicin.HCl | 1527

Anti-tumor antibiotic. Inhibitor of Reverse transcriptase and RNA Polymerase. Immunosuppressive agent. Highly effective myotoxin that inhibits topoisomerase II. Binds to Nucleic acids, presumably by specific intercalation into the DNA double helix, thereby inhibiting necleic acid synthesis. Induces apoptosis.

Doxorubicin is an anti-tumor antibiotic and an inhibitor of Reverse transcriptase and RNA Polymerase.

1527 | Doxorubicin.HCl DataSheet

Alternate Name/Synonyms: Adriamycin® hydrochloride, DOX, Hydroxydaunorubicin hydrochloride

Appearance: Orange-red powder

Formulation: N/A

CAS Number: 25316-40-9

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₇H₂₉NO₁₁ .HCl

Molecular Weight: 579.98

Cell-Permeable?: Yes

Purity: >98% by TLC

Solubilities: H₂O

Handling: Protect from moisture

Country of Origin: USA

Tag Line: Anti-tumor antibiotic

MDL Number: MFCD00077757

PubChem CID: 443939

SMILES: CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O.Cl

InChi: InChI=1S/C27H29NO11.ClH/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34;/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3;1H/t10-, 13-,15-,17-,22+,27-;/m0./s1

InChi Key: MWWSFMDVAYGXBV-RUELKSSGSA-N