DPEP1 Antibody (N-term) [APR04454G]

DPEP1 Antibody (N-term) [APR04454G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This DPEP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DPEP1.

Cellular Localisation: Apical cell membrane; Lipid-anchor, GPI-anchor. Cell projection, microvillus membrane; Lipid-anchor, GPI-anchor. Note=Brush border membrane {ECO:0000250|UniProtKB:P31429}

Molecular Weight: 45674

Clone: Polyclonal

Gene Name: DPEP1

Gene ID: 1800

Function: Hydrolyzes a wide range of dipeptides including the conversion of leukotriene D4 to leukotriene E4 (PubMed:2303490, PubMed:6334084, PubMed:31442408) . Hydrolyzes cystinyl-bis-glycine (cys- bis-gly) formed during glutathione degradation (By similarity) . Possesses also beta lactamase activity and hydrolytically inactivates beta-lactam antibiotics (PubMed:6334084) .

Summary: Tissue Location: Expressed in lung and kidneys.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Dipeptidase 1, Dehydropeptidase-I, Microsomal dipeptidase, Renal dipeptidase, hRDP, DPEP1, MDP, RDP