DPP IV Inhibitor, K 579 | 1963

Cell-permeable. A potent, slow binding dipeptidyl peptidase IV inhibitor with IC₅₀ values of 3, 5, 8, and 8 nM for rat, canine, human and monkey enzymes respectively. Acts as a long-acting hypoglycemic agent.

DPP IV Inhibitor, K 579 is a potent, slow binding dipeptidyl peptidase IV inhibitor with IC₅₀ values of 3, 5, 8, and 8 nM for rat, canine, human and monkey enzymes respectively. Acts as a long-acting hypoglycemic agent.

1963 | DPP IV Inhibitor, K 579 DataSheet

Alternate Name/Synonyms: (2S)-1-[[[4-Methyl-1-(2-pyrimidinyl)-4-piperidinyl]amino]acetyl]-2-pyrrolidinecarbonitrile

Appearance: Light brown solid

Formulation: N/A

CAS Number: 440100-64-1

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₇H₂₄N₆O

Molecular Weight: 328.41

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (~100 mM) or EtOH (~ 20 mM) or 1 eq. HCl (50 mM)

Handling: Protect from light and air

Country of Origin: USA

Tag Line: A potent DPP IV Inhibitor,

MDL Number: MFCD07364044

PubChem CID: 9818824

SMILES: CC1(CCN(CC1)C2=NC=CC=N2)NCC(=O)N3CCCC3C#N

InChi: InChI=1S/C17H24N6O/c1-17(21-13-15(24)23-9-2-4-14(23)12-18)5-10-22(11-6-17)16-19-7-3-8-20-16/h3,7-8,14,21H,2,4-6,9-11,13H2,1H3/t14-/m0/s1

InChi Key: JERPHRNGJBSFAP-AWEZNQCLSA-N