DprE1-IN-2 | B2295

DprE1-IN-2 is a potent inhibitor of decaprenylphosphoryl-D-ribose oxidase (DprE1) of Mycobacterium tuberculosis, an essential enzyme involved in cell wall metabolism, for which new promising molecules have proved efficacy as antitubercular agents.

DprE1-IN-2 is a potent inhibitor of decaprenylphosphoryl-D-ribose oxidase (DprE1) of Mycobacterium tuberculosis, an essential enzyme involved in cell wall metabolism, for which new promising molecules have proved efficacy as antitubercular agents.

B2295 | DprE1-IN-2 DataSheet

Alternate Name/Synonyms: 1-[[6-(dimethylamino)-5-methyl-4-pyrimidinyl]methyl]-N-(2-hydroxyethyl)-6-methyl-1H-pyrrolo[3,2-b]pyridine-3-carboxamide; MDK-3875

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 1615713-87-5

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₉H₂₄N₆O₂

Molecular Weight: 368.4

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A non-covalent inhibitor of decaprenylphosphoryl-D-ribose oxidase (DprE1)

MDL Number: N/A

PubChem CID: 90467014

SMILES: CC1=CC2=C(C(=CN2CC3=C(C(=NC=N3)N(C)C)C)C(=O)NCCO)N=C1

InChi: InChI=1S/C19H24N6O2/c1-12-7-16-17(21-8-12)14(19(27)20-5-6-26)9-25(16)10-15-13(2)18(24(3)4)23-11-22-15/h7-9,11,26H,5-6,10H2,1-4H3,(H,20,27)

InChi Key: BLNAAWXUNQHVNT-UHFFFAOYSA-N